|
|
New York, NY, February 1, 2006 – Today, the Foundation for Clinical Research in Inflammatory Bowel Disease announced that it awarded a clinical research grant to the IBD Center at the Mount Sinai School of Medicine in New York to study the prevention of pouchitis following surgery in ulcerative colitis. The study, entitled “Tinidazole and the Prevention of Pouchitis Following Ileal Pouch-Anal Anastomosis Surgery in Ulcerative Colitis,” will examine the effectiveness of the antibiotic Tinidazole in preventing pouchitis when taken at a low-dose immediately following surgery and continued for 12 months.
“We believe that clinical research is essential to understanding and managing IBD,” said Jane Present, co-founder and executive director of the Foundation for Clinical Research in IBD. “Through our Clinical Research Grants, we are delighted to be able to provide the funding for clinically relevant projects like the one at Mt. Sinai.”
Pouchitis is a potentially serious complication that affects approximately half of all ulcerative colitis patients who have ileal pouch anal-anastomosis surgery, also known as the J-pouch. The J-pouch is an option for ulcerative colitis patients whose colons have been removed due to severe disease that does not respond to medical therapy or the detection of pre-cancerous or cancerous lesions. Pouchitis is generally responsive to antibiotic therapy, however, nearly 10% of pouchitis patients develop a chronic form of the disease that can be disabling and, in rare cases, result in the removal of the pouch. Currently, there is no preventive therapy routinely given for pouchitis.
Ulcerative colitis, one of the diseases that collectively are known as IBD, affects over five hundred thousand Americans and is a chronic, life-long disease that has no known cause or cure.
The Foundation for Clinical Research in IBD is a non-profit organization that is dedicated to providing continued support to the IBD professional community, encouraging and enabling continued clinical research into IBD and its treatments and supporting patients and their families through education.
Back to top.
|
